As expected, the knockdown of dynamin 2 expression mediated by the siRNAs suppressed the MLV vector infections in mouse NIH3T3 (Fig. 7A), human TE671 (Fig. 7B), and rat XC cells (Fig. 7C), but not the CXCR4-tropic HIV-1 and VSV infections. The gene discussed is CXCR4; the disease is infection.