When comparing the mammary carcinomas to the age-matched untreated control mammary gland, the RMECs from mammary carcinomas showed increased expression of Integrin β1, Integrin α6, FAK, and pFAK (Fig. 5B), as well as decreased expression of Integrin β3 (Fig. 5B), SMA, and Thy-1. The gene discussed is SMN1; the disease is breast carcinoma.