At low cellular concentrations [0.5–1×105 cells/ml], 59M ovarian cancer cells potentiated PAR-1 [TRAP], PAR-4 [PAR4 agonist] and TxA2 receptor [Arachidonic Acid] mediated platelet activation [P-selectin expression], but had no effect on ADP, epinephrine, or collagen induced activation [Figure 4]. Here, F2RL3 is linked to ovarian cancer.