The two metastatic ovarian cancer cell lines; SK-OV-3 [1.5×106 cells/ml, 47±10.2% of platelets P-selectin positivity, n = 3] and 59M [1.5×106 cells/ml, 51±18% P-selectin positivity n = 6] induced the most significant platelet activation. The gene discussed is SELP; the disease is ovarian carcinoma.