CD58 and cancer: Increased expression was observed in genes for cancer associated proteases [KLK1], cell adhesion/migration molecules [ITGB2/LFA-1], and reduced expression of genes involved in maintaining genomic instability [GMNN], inhibition of gene transcription/expression [CCDC7B, ZNF271, ZNF706, LARP7, RNASEH2B], pro-apoptotic regulation [STK17B/DRAK2] and immune response/evasion [CD58/LFA3].