Pre-B-cell leukemia transcription factor 1 (PBX1) was upregulated in inflammation-associated PaSC's compared to tumor-associated PaSC's, while cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) expression was upregulated in tumor-associated PaSC's compared to that of inflammation-associated PaSC's [37]. The gene discussed is PBX1; the disease is neoplasm.