KRAS mutated lung cancer may be observed in mouse strains carrying oncogenic alleles of KRAS that can be activated only on a spontaneous recombination event in the whole animal [43], or after KRAS sporadic activation through Cre-lox mediated somatic recombination after adenoviral mediated delivery of Cre recombinase in lung epithelia [39]. The gene discussed is KRAS; the disease is lung carcinoma.