INS and fetal growth restriction: It showed that peak insulin level was elevated and insulin concentration descended much slower in IUGR group, with higher insulin levels at 60 and 120 min after glucose administration at 15 weeks of age (3.43±0.63 ng/ml vs 2.53±0.32 ng/ml; 2.66±0.68 ng/ml vs 1.86±0.25 ng/ml, P<0.05) (Table 1); AUCi, considered as the area under the insulin releasing curve, was also markedly elevated (6.02±0.81 ng/ml•h vs 4.45±0.56 ng/ml•h, P<0.05) (Fig. 5).