The strongest new pleiotropic signal in European Americans was for rs4420638 (P 1.7×10−57), located approximately 0.32 kilobases (kb) downstream of APOC1 and associated with elevated plasma glucose (P = 8.7×10−4), atherogenic dyslipidemia (1×10−31), vascular inflammation (P = 5×10−12), and central obesity (P = 1.2×10−6). This evidence concerns the gene APOC1 and Abdominal obesity.