APOA1 and Hypertension: However, significant interactions with the prudent diet score were found for all four SNPs for the outcome of MI (Table 3), with the strongest effect seen for the interaction of rs2383206 (unadjusted p = 0.0004, and adjusted for the risk factors apoB/apoA1, waist/hip ratio, diabetes, hypertension, and smoking, p = 0.018).