The Wnt receptor activity pathway (GO:0042813) was among the most enriched functional groups (p = 8.55E−13, FDR = 7.94E−11), with ninety lung cancer samples expressing at least one of the following seven components (FZD3; FZD4; FZD6; FZD7; FZD8; FZD10; RYK) at least 2.5-fold above the average of Group 2 samples. The gene discussed is FZD8; the disease is lung cancer.