PIM1 and cancer: Overexpression of PIM-1 has been reported in haematological malignancies and in many solid tumours, which suggests that blocking PIM-1 kinase activity may be a promising approach for cancer therapy (Eichmann et al, 2000; Cibull et al, 2006; Beier et al, 2007; Chen et al, 2008; Hogan et al, 2008).