ERBB2 and neoplasm: The clinically validated c-erbB2 immunohistochemistry analyses and ERBB2 FISH analyses supported and served as controls for the array CGH results of ERBB2 gene amplification found in the tumor cells harvested from the separate bone marrow aspirate, indicating an enrichment of such cells in the bone marrow metastasis which clearly progressed during the initial three courses of chemotherapy as shown on the computer tomography radiographs.