Again, none of the AEI-positive genes listed above was correlated with a SNP located in the region of the gene, although a SNP located on chromosome 1 was weakly correlated with expression of GNB1L mRNA in the set of AD brain samples (r2 = the contribution of SNP rs7527404 to the variance of transcript expression = 0.13). The gene discussed is GNB1L; the disease is Alzheimer disease.