Previous reports had not described the type of Th2 response TLR3- or TRIF-deficient mice develop during CVB3 myocarditis [11, 14], and since susceptibility to chronic autoimmune myocarditis is dependent on a Th2-type immune response [16, 17], we were interested in determining whether a shift had occurred. Here, TLR3 is linked to autoimmune myocarditis.