By day 7, IFNγ, CSF2, CXCL10, GZMB, PTGS2, TNFα, CD80, CCL22, IL12a, IL13, IL1b, IL6, NOS2, and CTLA4 were significantly upregulated in the tumor-bearing mice bladders and AGTR2 and GATA3 were downregulated. The gene discussed is CTLA4; the disease is neoplasm.