Figure 1(a), top right panel shows tumor bearing bladders harvested at day 7, when the tumors were small and at day 28 (bottom right panel) when the tumors were large. In all mice, an initial increase in urinary PSA secretion was observed at day 11 but later as some mice were cured, PSA secretion decreased, Figure 1(b). This evidence concerns the gene KLK3 and neoplasm.