GATA4 and coronary artery disorder: The product of GATA4 belongs to the zinc-finger family of transcription factors and, as the other GATA proteins, it binds to the 5′-(A/C/T)GATA(A/G)-3′ motif within its target sequences.16 The mammalian GATA4 gene was identified in a screen of zinc-finger encoding cDNAs in a mouse library,17 and it was first suspected to be implicated in CHD when a deletion18 and a duplication19 of the chromosomal segment in which it is contained were discovered in patients with cardiac malformation.