The skin specimens were classified into the following five categories on the basis of their morphological features by two pathologists (CLC and RAS)—normal skin (16 patients), recent scars (<30 days old; 28 patients), old scars (OC) (>30 days old; 27 patients), actinic keratosis (27 patients), and SCC (16 patients)—and scored according to the grading of staining for TRIM16 expression. Here, TRIM16 is linked to actinic keratosis.