BCL2 and sarcoma: Finally, as Bcl-2 diverts vascular cells from apoptosis and prolongs their survival [21, 29, 30, 42], its expression in advanced KS, coupled with a deregulated cellular proliferation by HIV, HHV8, and cellular factors [1, 2], may result in KS maintenance and/or the progression of the early angio-hyperplastic KS lesions into a true sarcoma.