Outcome can be summarized as follows: blood plasma lipoprotein levels; ECG test, indicator of severity of myocardial ischemia [18]; endothelium-dependent vessel relaxation (EDVR); histomorphological studies; expressions of endothelial nitric oxide synthase (eNOS) and vascular cell adhesion molecule 1 (VCAM-1) on coronary arteries, markers of endothelial function [19, 20]. This evidence concerns the gene NOS3 and myocardial ischemia.