EGFR and breast cancer: In another study of 564 tissue microarrays from primary tumors from premenopausal breast cancer patients who had been randomized to adjuvant tamoxifen or no adjuvant treatment, TNBCs show increased protein expression of epithelial growth factor receptor (EGFR) and VEGFR2, whereas the expression of VEGF-A is not a specific biomarker of TNBCs [27].