Female Sv129 mice injected with F9 teratocarcinoma cells and CD-1 nude mice injected with A673 rhabdomyoscarcoma cells were treated with either 1 mg20 g-1 clodrolip (initial dose 2 mg20 g-1), clodronate dissolved in phosphate buffer (67 mM) or anti VEGF Abs 0.5 mg20 g-1 i.v. or clodrolip and anti VEGF Abs in combination. This evidence concerns the gene VEGFA and teratocarcinoma.