CEP290 and Bardet-Biedl syndrome: There have been three different genes reported to cause both BBS and JS: CEP290, TMEM67, and INPP5E (in the case of INPP5E, mutations are associated with the related disorder MORM syndrome, which is probably a phenocopy of BBS) [Baala et al., 2007; Leitch et al., 2008; Bielas et al., 2009; Jacoby et al., 2009].