To assess whether NF-κB signaling was involved in the inhibition of AML cell growth by HF, we used stable transformant NB4 cells expressing a repressor form of Iκ-Bα, Iκ-Bα (A32/36) which acts like a constitutive repressor of NF-κB activation [31]. Here, NFKB1 is linked to acute myeloid leukemia.