CASP3 and mesothelioma: To determine the nature of this death in mesothelioma cells induced by H342, we have used fluorescent staining assay, Western blot, and caspase-3 activity assay to test cell morphological changes, caspase-3 activity, and expression of apoptosis-associated proteins during the cell death of H2373 mesothelioma cells treated by H342 for different times.