Thus, our findings in lung biopsies from patients with lung fibrosis are congruent with the results from cellular and animal models indicating that RSK induction and its phosphorylation of mouse C/EBPβ-Thr217 or human C/EBPβ-Thr266 in activated lung fibroblasts may be important in the development of human lung injury and fibrosis. Here, CEBPB is linked to pulmonary fibrosis.