EGFR and gastric cancer: Epidermal growth factor receptor is highly expressed in approximately one-third of advanced-stage gastric cancers (Nicholson et al, 2001; Rojo et al, 2006; Galizia et al, 2007; Liakakos et al, 2008), and the activation of EFGR may be involved in chemoresistance in solid tumours (Ciardiello and Tortora, 2001).