At the MLN, IFNγ, IL-6, KC (keratinocyte chemoattractant, CXCL1), and MCP-1 (monocyte chemoattractant protein-1, CCL2) are increased following a SC infection, but remain at control levels following an IN infection; Rantes (regulated upon activation normal T cell expressed and secreted, CCL5), however, is increased significantly at day 6 and day 7 in mice infected by the SC and IN routes [31]. The gene discussed is IFNG; the disease is infection.