Another kind of dissimilarity between different NB cell lines consists in lower activity of caspase-1 in BE(2)-m17 and SK-n-MCIXC cells (as compared to that in Lan-1 cells) that have not been exposed to LCA; importantly, LCA further and significantly reduces the activity of this inflammatory caspase in BE(2)-m17 and SK-n-MCIXC, but not in Lan-1 (Suppl. The gene discussed is CASP1; the disease is neuroblastoma.