SLCO1B1 and myopathy: The association between SLCO1B1 rs4149056 with myopathy (odds ratio: 4.5 - 95% CI 2.6 to 7.7, per copy of the C allele; and odds ratio: 16.9 - 95% CI 4.7 to 61.1, among CC homozygotes as compared with TT genotypes) was observed in 85 subjects with myopathy taking 80 mg of simvastatin daily as part of a trial involving 12,000 participants; plus replication in a trial of 40 mg of simvastatin daily involving 20,000 participants [9].