SLCO1B1 and myopathy: SLCO1B1 rs4149056 was associated with an odds ratio for myopathy of 4.5 (95% CI, 2.6 to 7.7) per copy of the C allele and 16.9 (95% CI, 4.7 to 61.1) among CC homozygotes as compared with the TT genotype, in a genome-wide association study plus replication in a trial of simvastatin 40 mg daily involving 20,000 participants [9].