However, melanoma-derived tumor growth rate in mice injected with WM278 cells overexpressing GFP-Nck2 (N7 and N14) was greatly enhanced compared with tumor found in mice injected with WM278 cells parental or overexpressing GFP (C2) (Figure 10B), suggesting that increased expression level of Nck2 promotes primary melanoma-derived tumor growth rate. The gene discussed is NCK2; the disease is melanoma.