Among more than 470 polymorphisms in the VDR gene [11, 17], there may be six polymorphisms including the Fok1, Cdx2, Bsm1, Apa1, and Taq1 SNPs, and Poly(A) microsatellite to be frequently studied in relation to risk of cancer including prostate cancer. The gene discussed is VDR; the disease is Familial prostate cancer.