The percentage of vessel and muscle invasion by STAT3-silenced tumors was 22.22% (2/9) and 33.33% (3/9) compared to 60% (6/10), 80% (7/10) and 70% (7/10), 80% (8/10) in SW1990 tumor and negative control tumor, respectively. The gene discussed is STAT3; the disease is neoplasm.