The mean IL-1β level in afebrile status epilepticus attacks in intractable epilepsy patients was at a 11.7-fold increase higher than that of the afebrile controls (23.4 vs. 2.0 pg/mL) and a 7.5-fold increase higher than of fever only controls (Table 3, 23.4 vs. 3.1 pg/mL, p < 0.05). Here, IL1B is linked to status epilepticus.