HMGB1 and Febrile seizure (within the age range of 3 months to 6 years): In order to determine whether active inflammation, including HMGB1 and pro-inflammatory cytokines, occurs in children with febrile seizures and pediatric epilepsy, we analyzed cytokine profiles in the serum of child patients with febrile seizures or epilepsy and assessed the correlation between cytokine levels and febrile seizures.