By multivariate analysis, risk factors for cryptococcal meningitis included: CD4 counts of less than 100 cells/mm3 (OR 28.0, 95% CI 2.9-272.0), altered mental status (OR 25.3, 95% CI 5.1-126.2), neck stiffness (OR 10.2, 95% CI. Here, CD4 is linked to Cryptococcal meningitis.