KDM1A and colonic neoplasm: The dysregulation of LSD1 activity possesses a significant impact on human carcinogenesis [8] and has been implicated in maintenance of a variety of cancer types, such as neuroblastoma [19], breast cancer [20], [21], colon cancer [22], etc. Moreover, the expression of LSD1 is closely correlated with the relapse of prostate cancer during therapy [23], [24].