PHGDH and malaria: As for the set of the 45 proteins identified, the presence of several of them was somehow expected considering that they belong to families that have already been characterized as good malaria antigen candidates; specifically, 6 proteins belonged to the serine repeat antigen family (SERA) which is considered a vaccine candidate antigen for P. falciparum malaria due to the immunogenicity conferred in rats by one of them when expressed as a recombinant protein [33].