There were no significant difference in age, gender, diabetes, left ventricular ejection fraction, blood pressure, triglycerides, total cholesterol, LDL cholesterol, HbA1C, serum creatinine, urea nitrogen, uric acid, medications treatment such as angiotensin converting enzyme inhibitors/angiotensin II type 1 receptor blockers (ACEIs/ARBs), oral hypoglyceimic agents, insulin and antibiotics between the two groups. Here, INS is linked to diabetes mellitus.