After discovering that it was associated with Fanconi anemia [6], they screened for mutations in RAD51C in 1100 hereditary breast (HBC) and HBOC families, hypothesizing that it would be similar to BRIP1 and BRCA2 in which biallelic mutations cause Fanconi anemia and monoallelic mutations cause HBOC. The gene discussed is BRCA2; the disease is Fanconi anemia.