GPT and steatosis: More strikingly, post-operative liver injury as quantified by AST (Figure 7C) and ALT (Figure 7D) was significantly decreased by 57% (P = 0.020) and 44% (P = 0.032), respectively, after 24 hours, and by 55% (P = 0.036) and 45% (P = 0.022), respectively, after 48 hours in the group of diet-induced obese animals that had their steatosis reversed following Marimastat treatment, compared to controls.