Within the top 100 ranked genes, genes implicating susceptibility to RA (CD247, IL2RB and IL2) and to other autoimmune diseases (CD80, FCGR2A, FCGR2B, ICAM1, JAK2, LYN, NFKBIA, PTPN11, STAT3 and TRAF3IP2) are enriched. The gene discussed is ICAM1; the disease is rheumatoid arthritis.