Of the up-regulated miRNAs in the metastatic line, miR-9 has been reported to target E-cadherin [64] and CDH1, the E-cadherin-encoding messenger RNA [65]; overexpression of miR-9 in non-metastatic breast tumor cells enables such cells to form pulmonary micrometastases in mice [65]. The gene discussed is CDH1; the disease is breast neoplasm.