Further we would suppose that KC, which are capable of both pinocytosis and phagocytosis, would be taking up virus by pinocytosis were the particles monodisperse, but the appearance of some clumped Cy3-virus in KC (Fig. 5) suggests that the labeling process may induce limited aggregation which by size alone would encourage phagocytosis by KC. Here, CALCA is linked to keratoconus.