This response was severely curtailed in hosts undergoing protracted or chronic LCMV infections as only 11-35% and 0.9-9%, respectively, of the GP33-specific CD8 T cells became IFN-γ positive following LM co-infection, and similar trends were observed for the GP276 viral epitope-specific responses (Fig. 7E). The gene discussed is IFNG; the disease is lymphangioma.