IL1B and neoplasm: To determine whether the pro-inflammatory cytokine IL-1β may induce the expression of cytokines of the innate immune response in a HR tumor cell line, SK-N-SH cells were cultured in the presence or absence of IL-1β (600 ng/0.25 × 106 cells) for 24 or 72 hs, and supernatants were subjected to multiplex cytokine array analysis while cells were analyzed by flow cytometry.