Recently, Metlapally et al. [49] reported a genetic association between the three single nucleotide polymorphism (SNP)s rs6214, rs10860860, and rs2946834 and familial myopia in a large, international cohort of myopia pedigrees of Caucasian origin, suggesting that insulin-like growth factor 1 (IGF-1) may be a candidate gene for HM. The gene discussed is IGF1; the disease is myopia.