KIT and gastrointestinal stromal tumor: Because GIST harboring KIT exon 11 mutations appeared to be more sensitive to imatinib treatment than GIST of other genotypes in the metastatic setting [11] and, shown more recently, in the adjuvant setting [12], patients with KIT exon 11 mutations at high risk of recurrence would be most likely to benefit from adjuvant treatment with imatinib.