NME1 and neoplasm: For instance, hemopexin protein was found elevated in the serum of patients with HL [29]; eosinophil peroxidase has already been used for radio-immunodetection of Hodgkin's disease [30]; coagulation factor XIII was found to be expressed by macrophages and involved in the stabilization of fibrin deposits in the tumour stroma of HL samples [31]; and nucleoside diphosphate kinase A expression was found to be a prognostic factor for classical HL [32].