TNF and hepatocellular carcinoma: Of the “Th1/effector” cytokines and chemokines in the cocultures of CD4+ T cells and DC groups (IFN-γ, IP-10, TNF-α, IL-2), IFN-γ was notably higher in the two HD and one HCC (A1) coculture of CD4+ with AdV/DC, as compared to the other DC conditions.