Mutations in SCN5A, coding for the α-subunit of the ion channel conducting the depolarising INa -current [4,5], and in ABCC9 [6], coding for the cardiac specific SUR2A subunit of the KATP potassium channel, have been associated with dilated cardiomyopathy (DCM). This evidence concerns the gene SCN5A and familial dilated cardiomyopathy.