NR4A1 and metastatic malignant neoplasm in the lymph nodes: Although the overall survival rate of breast cancer patients did not correlate with TG2 expression levels, patients with TG2-upregulated tumors showed significantly shorter relapse-free survival and distant metastasis-free survival, after adjusting for known prognostic factors such as tumor size, lymph node metastasis, age, and hormone-receptor status.