Next to test whether NSCLC cell specific N-CoR loss was linked to ER stress as observed in APL, level of ER stress across NSCLC cells was compared to that of DMS-79 cells by measuring the levels of GRP78 and PDI proteins, two bona fide markers of ER stress [24], [25]. The gene discussed is HSPA5; the disease is acute promyelocytic leukemia.